Presenter(s): Gowthami Thota Title: Comparison of Cannabidiol containing Topical Formulation vs Coated 3D Printed Microneedles for Trans-dermal Diffusion using Human Cadaver skin Developed under the guidance of Dr. Scott Asbill and Dr. Mali Gupta , College of Pharmacy & Health Sciences
Micro-needles (MN) are gaining a lot attention these days because of painless administration and providing optimal diffusion due to formation of temporary micro pores. There are many methods in formulating a MN patch. One among them is 3D Printing Process, where the use of a STL (Stereo lithography) file is used for the formation of an 3D printed object. Each 3D printed MN patch have 48 needle projections attached to the base substrate of 15×15×1 mm. The height of each MN will be 1 mm and the base cross-section of 1×1 mm. The incorporation of Cannabidiol (CBD) will be done using modified dip coating technique to work on a laboratory scale. Topical formulation of CBD will be prepared by dissolving the drug in sesame oil as standard. In-vitro studies will be carried out using Cadaver human skin as the experimental membrane.
Contact
113 Main Street
PO Box 98
Buies Creek, NC 27506 Directions
