9th Annual WML Academic Symposium

Time: 11:30
Room: 224
Presenter(s): Sukanya Nagfernandes
Title: Formulation, Comparison, and Evaluation of Teeth Whitening Film Strips
Developed under the guidance of Dr. Mali R.Gupta , Pharmaceutical Science

Oral health and hygiene plays a critical role in the overall well-being of an individual. The demand for whiter teeth is not only taking the social media by storm, but is also shifting the paradigm of practicing dentistry. It has also made people conscious about the importance of oral health and hygiene. Undergoing periodic teeth whitening regimen could help prevent gingivitis, periodontitis and potential loss of teeth, thus contributing greatly towards establishing oral hygiene (Margeas). Alongside maintaining oral health and hygiene, a set of pearly whites can boost an individual’s self-esteem, appearance and their longevity. An OTC (Over-The-Counter) Dentin® strip for teeth whitening is not only patient compliant, but also facilitates a quick onset of action and results in visibly whiter teeth. The objective of the experiment conducted was to formulate, compare and evaluate varying concentrations of Hydrogen peroxide to Carbamide peroxide, in a similar bio adhesive delivery system in order to strengthen the use of the later as a safer, less sensitive to surface microhardness and equally effective dentin bleaching agent. The comparison and evaluation for their ability to whiten teeth was conducted using stained hard-boiled eggs and measured using the renowned, VITA Classical Shade guide. (VITA, 2018) (Bouassida, M. 2017). The method employed involved formulating various concentrations of Hydrogen peroxide, 6.5% w/w and 13% w/w against an equivalent Hydrogen peroxide releasing analog, Carbamide peroxide 18.57% w/w and 37.14% w/w respectively. The evaluation of these four batches were done using extrinsically stained hard-boiled white eggs and the whitening efficiency was measured using a VITA Classical shade guide (VITA, 2018) (Margeas). All the four batches were also evaluated for thickness, pH, weight variation and folding endurance.