9th Annual WML Academic Symposium

Presenter(s): Ninad Mukadam
Title: Formulation and Evaluation of Econazole Nitrate Transferosomes
Developed under the guidance of Dr. Antoine Al-Achi , College of Pharmacy & Health Sciences

Transferosomes are novel vesicular drug carrier system made up of phospholipid, surfactant, and ethanol. Econazole nitrate is used as an antifungal agent and its antifungal activity of econazole nitrate is limited because of its poor water solubility and thus a novel formulation strategy of transferosomes will be used. Econazole nitrate loaded transferosomes will be prepared by conventional thin film evaporation and hydration method using a rotary evaporator. Transferosomes will be characterized for vesicle size distribution, zeta potential, percent entrapment of econazole nitrate, shape of the vesicles using scanning electron microscopy (SEM), and residual chloroform and methnaol content. Transferosomes will be subjected to stability studies at 4 °C and 20 °C at time intervals of 0 days, 15 days, 30 days, and 45 days.