9th Annual WML Academic Symposium

Presenter(s): Ina Lico, Dominic Putala Saadiya Sehareen, Robert Shebiro
Title: Cadaveric Case Study: Squamous Cell Lung Carcinoma with a Review of Targeted Therapies
Developed under the guidance of Dr. Bonnie Brenseke and Dr. Terence Mitchell , School of Osteopathic Medicine

During dissection of a 56-year-old male, a 3cm solitary nodule was found in the lower lobe of the left lung. Dissection revealed a tan, soft, and friable material located peripherally with central cavitation and anthracnosis. Histological evaluation revealed squamous epithelium with laminated layers of keratin, keratin pearls, keratinized intercellular bridges, pleomorphisms, and mitotic figures indicating small cell carcinoma. Although the cause of death is unknown, it is unlikely due to the solitary nodule. A review of current targeted therapies and immunotherapies is described for potential treatment upon further immunohistochemistry evaluation of the nodule