Statin Prescribing in Diabetic Patients in NHAMCS and NAMCS Databases During the Years 2005-2010
by Brandy R. Pauff, Victoria Lancaster
Developed under the guidance of:
Dr. Beth S. Sutton, Dr. Michael Jiroutek, and Dr. Melissa Holland
Clinical Research
In 2008, the American Diabetes Association (ADA) recommended all diabetics >40 years with cardiovascular disease (CVD) or >1 CVD risk factor(s) be prescribed a statin. This study assessed statin use in the National Hospital Ambulatory Medical Care Survey-Outpatient Department (NHAMCS-OPD) and National Ambulatory Medical Care Survey (NAMCS) for 2005-2007 and 2008-2010 for adherence to ADA guidelines. A retrospective, cross-sectional, observational design included diabetics >18 years in NHAMCS-OPD or NAMCS between 2005-2010 without statin contraindications. The study was IRB-exempt as it used only publicly available, de-identified data from the Centers for Disease Control and Prevention. Chi-square tests were conducted to analyze the proportion of statins (p<0.05 significant). A multivariate logistic regression model included all variables with an overall chi-square test p-value <0.2. Odds ratios (OR) and 95% confidence intervals (CI) were reported. No association between statin use and year (2008-2010 vs. 2005-2007) was identified (OR 1.17, 95% CI 0.97-1.40). The following groups were significantly less likely to receive a statin: 18-39 years (vs. 40-64 years, OR 0.51, 95% CI 0.36 – 0.73) and Hispanics (vs. non-Hispanics, OR 0.79, 95% CI 0.62-0.99). Patients with the following diagnoses were significantly more likely to receive a statin: hyperlipidemia (vs. no hyperlipidemia, OR 4.17, 95% CI 3.46-5.03) and hypertension (vs. no hypertension, OR 1.26, 95% CI 1.08-1.48). Statin receipt is not increasing and only a small percentage of patients receive a statin as recommended (29.3%). Adjusting for covariates, ethnicity, age, hypertension and hyperlipidemia were significant predictors of a statin. This study highlights the need to determine the underlying reasons for low statin prescribing, and to identify the determinants relating to treatment disparity in certain groups of diabetic patients.
Contact
113 Main Street
PO Box 98
Buies Creek, NC 27506 Directions